HCID 67108470, compound → HCID 58237245, compound

Participants

Reaction Steps

4-(7-Benzyloxycarbonylamino-1-oxo-2-aza-spiro[4.5]dec-2-yl)-piperidine-1-carboxylic acid tert-butyl ester (0.75 g, 1.54 mmol) in methanol (50.0 mL) was shaken under hydrogenated at 50 psi and rt for 2.5 hrs. The catalyst was filtered off, and the filtrate was concentrated to afford 0.42 g (77%) of the title compound. LC-MS (method C): RT: 0.94 min; ESI-MS m/z: 352 (M+H)+. It was used in the next step without further purification.

Provenance & Evidence