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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 472270Generated: October 30, 2026

1-(4-Bromophenyl)piperidine → HCID 49838267, compound

https://huagongshe.com/reaction/472270

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Bromophenyl)piperidineHCID 7016460—
Reactant8-(4-Methanesulfonyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamineHCID 57502376—
ProductHCID 49838267HCID 49838267—

Reaction Steps

[8-(4-Methanesulfonyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-(4-piperidin-1-yl-phenyl)-amine was prepared from 8-(4-methanesulfonyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine (100.0 mg, 0.3468 mmol) and 1-(4-bromo-phenyl)-piperidine (110.0 mg, 0.4581 mmol) in a manner analogous to Step 2d. The title compound was isolated as a yellow solid (0.039 g, 25%). MP=229-234° C. 1H NMR (400 MHz, CDCl3, δ, ppm):

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08633173B2
Source datasetuspto-grants-2014_01
ORD IDord-d37639f4c1b744f89ba72f50194acce9
Source noteuspto-grants-2014_01