HuagongsheHuagongshe Chemistry Print Report · For research reference only
(+-)-2-(Aminomethyl)-1-N-Boc-pyrrolidine → HCID 67479012, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (+-)-2-(Aminomethyl)-1-N-Boc-pyrrolidine | HCID 2756484 | — |
| Reactant | 8-Bromo-2-chloro-[1,2,4]triazolo[1,5-a]pyridine | HCID 67481370 | — |
| Product | HCID 67479012 | HCID 67479012 | — |
Reaction Steps
2-[(2-Chloro-[1,2,4]triazolo[1,5-a]pyridin-8-ylamino)-methyl]-pyrrolidine-1-carboxylic acid tert-butyl ester was prepared from 8-bromo-2-chloro-[1,2,4]triazolo[1,5-a]pyridine (500.0 mg, 2.151 mmol) and 2-aminomethyl-pyrrolidine-1-carboxylic acid tert-butyl ester (475.0 mg, 2.372 mmol) in a manner analogous to Example 2d. Product isolated as a yellow viscous oil (0.411 g, 54%). MS=374, 376 (MH)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08633173B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-a1e5a654ba774e1fbbe7462f2a1ff385 |
| Source note | uspto-grants-2014_01 |