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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 472599Generated: October 30, 2026

2-chloro-N,N-dimethylacetamide → HCID 59612525, compound

https://huagongshe.com/reaction/472599

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-chloro-N,N-dimethylacetamideHCID 75886—
ReactantHCID 59612463HCID 59612463—
ProductHCID 59612525HCID 59612525—

Reaction Steps

2-(4-{4-[8-(4-difluoromethyl-2-methoxy-phenyl)-[1,2,4]-triazolo[1,5-a]pyridin-2-ylamino]-phenyl}-piperidin-1-yl)-N,N-dimethyl-acetamide was prepared from [8-(4-difluoromethyl-2-methoxy-phenyl)-[1,2,4]-triazolo[1,5-a]pyridin-2-yl]-(4-piperidin-4-yl-phenyl)-amine (0.160 g, 0.356 mmol) and 2-chloro-N,N-dimethyl-acetamide (0.055 mL, 0.534 mmol) in a manner analogous to Example 313 to give product (0.035 g, 18%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08633173B2
Source datasetuspto-grants-2014_01
ORD IDord-61673a4e0204407a8a1e091ec3e722a7
Source noteuspto-grants-2014_01