HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl (4-{[(4,4-difluorocyclohexyl)methyl]amino}-3-nitrophenyl)carbamate → HCID 57723210, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl (4-{[(4,4-difluorocyclohexyl)methyl]amino}-3-nitrophenyl)carbamate | HCID 57723212 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 57723210 | HCID 57723210 | — |
Reaction Steps
Following the same procedure as in Step D of Example 4 using methyl (4-{[(4,4-difluorocyclohexyl)methyl]amino}-3-nitrophenyl)carbamate (200 mg, 0.583 mmol) and a catalytic amount of 10% Pd/C in 20 mL of EtOAc. Yield: 185 mg (99%). MS (ESI) (M+H)+ 314.29.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08633235B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-3edb10d63be44ae1b7e97e2cc64738e4 |
| Source note | uspto-grants-2014_01 |