Sarcosine → HCID 131731153, compound

HRID 473119Notes

Reaction equation

HRID 473119 reaction equation
[C:1]([O:5][C:6]([C:9]([C:12]([O:15][C:16]([C:19](OC)=[O:20])([F:18])[F:17])([F:14])[F:13])([F:11])[F:10])([F:8])[F:7])([F:4])([F:3])[F:2].[NH:23]([CH2:25][C:26]([OH:28])=[O:27])[CH3:24].[OH-].[K+:30]>C(O)(C)C>[C:1]([O:5][C:6]([C:9]([C:12]([O:15][C:16]([C:19]([N:23]([CH2:25][C:26]([O-:28])=[O:27])[CH3:24])=[O:20])([F:18])[F:17])([F:14])[F:13])([F:10])[F:11])([F:7])[F:8])([F:3])([F:4])[F:2].[K+:30]

Participants

5

Reactant 3

HCID 1088SarcosineHCID 14797Potassium HydroxideHCID 44604053HCID 44604053, compound

Product 1

HCID 131731153HCID 131731153, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Conditions

Temperature
60 °C

Procedure

In a three-necked 100-mL flask fitted with a stirrer, thermometer, and condenser were placed 18 grams (0.05 mole) of CF3OCF2CF2CF2OCF2C(O)OCH3, prepared in Example 1, Part A, and dry sarcosine (4.5 grams, 0.05 mole). The reaction mixture was heated under nitrogen at 60° C. using a heating mantle for 48 hours and then cooled to about 30° C. Isopropanol (23 grams) and potassium hydroxide (2.8 grams, 0.05 mole) were added to provide a solution of CF3OCF2CF2CF2OCF2C(O)N(CH3)CH2C(O)O—K+.

Workup

  1. customIn a three-necked 100-mL flask fitted with a stirrer
  2. customthermometer, and condenser were placed
  3. customfor 48 hours
  4. temperaturecooled to about 30° C

Sources & evidence

ORD record
ord-96fe36ebf86e4b63b647033cf063efc5
Source dataset
uspto-grants-2014_01
Patent number
US08633288B2

Reaction notes

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