Hydrazine hydrate (1:1) → 6-Bromo-1,4-phthalazinedione

HRID 47316Notes

Reaction equation

HRID 47316 reaction equation
O.[NH2:2][NH2:3].[Br:4][C:5]1[CH:6]=[C:7]2[C:12](=O)[O:11][C:9](=[O:10])[C:8]2=[CH:14][CH:15]=1>C(O)C>[Br:4][C:5]1[CH:6]=[C:7]2[C:8](=[CH:14][CH:15]=1)[C:9](=[O:10])[N:3]=[N:2][C:12]2=[O:11]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 665904-Bromophthalic anhydride

Product 1

HCID 227446166-Bromo-1,4-phthalazinedione

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

96.9 ml hydrazine monohydrate was added to a mixture of 20 g 4-bromophthalic anhydride and 400 ml ethanol, and the mixture was heated under reflex for 8 hr. After cooling, the resulting precipitates were collected by filtration to give 28 g of 6-bromo-1,4-phthalazinedione.

Workup

  1. temperaturethe mixture was heated under reflex for 8 hr
  2. temperatureAfter cooling
  3. customthe resulting precipitates
  4. filtrationwere collected by filtration

Sources & evidence

ORD record
ord-94ba53db053a4c8a95bd24f9098b8ee6
Source dataset
uspto-grants-2004_03
Patent number
US06699870B2

Reaction notes

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