HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 67361741, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | 2-[2-(3-Chlorophenyl)-ethyl]-4-methoxybenzoic acid | HCID 67359984 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 67361741 | HCID 67361741 | — |
Reaction Steps
For the synthesis of the title compound, 16.6 g (0.057 mol) of [2-(3-chlorophenyl-ethyl]-4-methoxybenzoic acid, 7.25 g (0.06 mol) of SOCl2, 250 ml of methylene chloride and 10 g of AlCl3 (0.075 mol) are employed in method K. Purification is carried out by column chromatography (flash; SiO2; hexane 90%/ethyl acetate 10%). C16H13ClO2(Mr=272.73)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08633312B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-40e971a28215435eb6d3358ab1542417 |
| Source note | uspto-grants-2014_01 |