Hydrogen Bromide → HCID 67359779, compound

HRID 473456Notes

Reaction equation

HRID 473456 reaction equation
[Cl:1][C:2]1[CH:19]=[CH:18][C:5]2[C:6](=[O:17])[C:7]3[CH:14]=[CH:13][C:12]([O:15]C)=[CH:11][C:8]=3[CH2:9][CH2:10][C:4]=2[CH:3]=1.Br>C(O)(=O)C>[Cl:1][C:2]1[CH:19]=[CH:18][C:5]2[C:6](=[O:17])[C:7]3[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][C:8]=3[CH2:9][CH2:10][C:4]=2[CH:3]=1

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 67361741HCID 67361741, compound

Product 1

HCID 67359779HCID 67359779, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

For the synthesis of the title compound, 1.0 g (4.87 mmol) of 2-chloro-8-methoxy-10,11-dihydrodibenzo[a,d]cyclohepten-5-one, 10 ml of HBr (48%, aqueous) and 10 ml of glacial acetic acid are employed in method L. C15H11ClO2(Mr=258.71)

Sources & evidence

ORD record
ord-ebe5626a900b4b4eacf44bde10e8aa82
Source dataset
uspto-grants-2014_01
Patent number
US08633312B2

Reaction notes

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