Potassium Carbonate → HCID 67361136, compound

HRID 473461Notes

Reaction equation

HRID 473461 reaction equation
[Cl:1][C:2]1[CH:18]=[CH:17][C:5]2[C:6](=[O:16])[C:7]3[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][C:8]=3[CH2:9][CH2:10][C:4]=2[CH:3]=1.Cl.Cl[CH2:21][CH2:22][N:23]1[CH2:28][CH2:27][O:26][CH2:25][CH2:24]1.C([O-])([O-])=O.[K+].[K+]>C(#N)C>[Cl:1][C:2]1[CH:18]=[CH:17][C:5]2[C:6](=[O:16])[C:7]3[CH:14]=[CH:13][C:12]([O:15][CH2:21][CH2:22][N:23]4[CH2:28][CH2:27][O:26][CH2:25][CH2:24]4)=[CH:11][C:8]=3[CH2:9][CH2:10][C:4]=2[CH:3]=1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 77210Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1)HCID 67359779HCID 67359779, compound

Product 1

HCID 67361136HCID 67361136, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

For the synthesis of the title compound, 0.44 g (1.69 mmol) of 2-chloro-8-hydroxy-10,11-dihydrodibenzo[a,d]cyclohepten-5-one, 0.345 g (1.86 mmol) of 4-(2-chloroethyl)morpholine hydrochloride and 0.93 g (6.75 mmol) of K2CO3 in 15 ml of acetonitrile are reacted by method Q. C21H22ClNO3(Mr=371.87)

Sources & evidence

ORD record
ord-84220c5aec17455aa87094596fde0e3e
Source dataset
uspto-grants-2014_01
Patent number
US08633312B2

Reaction notes

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