HCID 67359760, compound → 3-Acetamido-8-nitro-6H-dibenzo[b,e]oxepin-11-one

HRID 473484Notes

Reaction equation

HRID 473484 reaction equation
[C:1]([NH:4][C:5]1[CH:6]=[C:7]([CH:22]=[CH:23][CH:24]=1)[O:8][CH2:9][C:10]1[CH:18]=[C:17]([N+:19]([O-:21])=[O:20])[CH:16]=[CH:15][C:11]=1[C:12]([OH:14])=O)(=[O:3])[CH3:2]>S1(CCCC1)(=O)=O>[C:1]([NH:4][C:5]1[CH:24]=[CH:23][C:22]2[C:12](=[O:14])[C:11]3[CH:15]=[CH:16][C:17]([N+:19]([O-:21])=[O:20])=[CH:18][C:10]=3[CH2:9][O:8][C:7]=2[CH:6]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 1

HCID 67359760HCID 67359760, compound

Product 1

HCID 673606313-Acetamido-8-nitro-6H-dibenzo[b,e]oxepin-11-one

Reagents, catalysts & solvents 1

HCID 31347SulfolaneSolvent

Procedure

In accordance with general method W, 0.80 g (2.42 mmol) of (4) is partly dissolved in 10 ml of sulfolane at 100° C. 15 ml (30.0 g) of polyphosphoric acid are then added to the reaction mixture. Yield: 0.50 g (66.2%); melting point: 171.4° C.

Sources & evidence

ORD record
ord-69d7417c44904d0f9810262a54dfbbb1
Source dataset
uspto-grants-2014_01
Patent number
US08633312B2

Reaction notes

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