HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → 8-Amino-3-(4-fluoro-2-methoxyphenylamino)-6H-dibenzo[b,e]oxepin-11-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | 8-Nitro-3-(4-fluoro-2-methoxyphenylamino)-6H-dibenzo[b,e]oxepin-11-one | HCID 67360627 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 8-Amino-3-(4-fluoro-2-methoxyphenylamino)-6H-dibenzo[b,e]oxepin-11-one | HCID 45280744 | — |
Reaction Steps
In accordance with general method Y, 0.30 g (1.32 mmol) of tin(II) chloride dihydrate is dissolved in 15 ml of ethanol, and 0.07 g (0.19 mmol) of (16) is added. Yield: 0.042 g (60.6%); melting point: 38.9° C.; C21H17FN2O3 (Mr=364.38); LC 18.82 min
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08633312B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-e01bfe619b4f420993fcbc4aefaeb3d6 |
| Source note | uspto-grants-2014_01 |