HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → N,N,N-trimethyl-o-nitrophenylmethanaminium iodide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | N,N-dimethyl-2-nitrobenzylamine | HCID 420851 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N,N,N-trimethyl-o-nitrophenylmethanaminium iodide | HCID 86676882 | 167.6% |
Reaction Steps
The mixture of 57b (0.18 g, 0.5 mmol) and iodomethane (0.71 g, 5 mmol) in anhydrous CH2Cl2 (5 mL) was stirred for 12 h at r. t., then added additional iodomethane (0.71 g, 5 mmol) and continuously stirred for 12 h. After evaporation, the residue was dispensed with CH2Cl2 and filtered to give 58b (0.27 g, 84%) as yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08637490B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-248a1c7ada74457faec3cfb183cb3ff4 |
| Source note | uspto-grants-2014_01 |