反应详情

A flask was charged with a stir bar, 4-bromo-2-fluoro-pyridine (2.00 g), and hydrazine hydrate (5.5 mL). The resulting mixture was vigorously stirred at room temperature overnight. Then, 4 M aqueous NaOH solution (5 mL) and water (10 mL) were added and the mixture was vigorously stirred for another 10 min. The precipitate was separated by filtration, washed with water, and dried at 50° C. The title compound was isolated as a colorless solid.

1. additionA flask was charged with a stir bar
2. stirringthe mixture was vigorously stirred for another 10 min
3. customThe precipitate was separated by filtration
4. washwashed with water
5. customdried at 50° C