HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 46836600, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 58477533 | HCID 58477533 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 46836600 | HCID 46836600 | — |
Reaction Steps
918 mg (1.65 mmol) of 2-[4-(1-{3-[5-(2-morpholin-4-ylethoxy)pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydropyridazin-3-yl)pyrazol-1-yl]ethyl acetate are dissolved in 5 ml of methanol, 73 mg (1.81 mmol) of sodium hydroxide are added, and the mixture is stirred at room temperature for 15 h. A precipitate forms in the process, which is filtered off with suction and triturated with methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08637518B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-2ab2acdb84154e7a92b76c2efdf71e2c |
| Source note | uspto-grants-2014_01 |