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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 474216Generated: October 31, 2026

Sodium Hydroxide → HCID 46836600, compound

https://huagongshe.com/reaction/474216

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 58477533HCID 58477533—
SolventMethanolHCID 887—
ProductHCID 46836600HCID 46836600—

Reaction Steps

918 mg (1.65 mmol) of 2-[4-(1-{3-[5-(2-morpholin-4-ylethoxy)pyrimidin-2-yl]-benzyl}-6-oxo-1,6-dihydropyridazin-3-yl)pyrazol-1-yl]ethyl acetate are dissolved in 5 ml of methanol, 73 mg (1.81 mmol) of sodium hydroxide are added, and the mixture is stirred at room temperature for 15 h. A precipitate forms in the process, which is filtered off with suction and triturated with methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08637518B2
Source datasetuspto-grants-2014_01
ORD IDord-2ab2acdb84154e7a92b76c2efdf71e2c
Source noteuspto-grants-2014_01