反应详情

3-acetyl4-methylthiobenzoic acid methyl ester (0.43 g) in water:methanol (1:3, 290 ml) containing sodium hydroxide (0.2 g) was stirred for 6 h. Methanol was removed at reduced pressure and the solution acidified with conc. hydrochloric acid to give 3-acetyl-4-methylthiobenzoic acid (0.32 g) after filtration. m/z (API+): 211 (MH+).

1. customMethanol was removed at reduced pressure