反应详情

Sodium thiomethoxide (0.469 g) was added to a solution of 2-methoxy-5-nitrobenzyl bromide (1.5 g) in dimethylformamide (25 ml). The mixture was stirred for 16 h, solvent removed at reduced pressure and the residue dissolved in ethyl acetate and washed with water and brine, dried (Na2SO4) and solvent removed at reduced pressure to give the title compound (1.2 g) as a yellow solid

1. customsolvent removed at reduced pressure
2. dissolutionthe residue dissolved in ethyl acetate
3. washwashed with water and brine
4. dry with materialdried (Na2SO4) and solvent
5. customremoved at reduced pressure