HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-7-methylisoquinoline → 4-[3-(7-Methyl-isoquinolin-1-ylamino)-benzylamino]-quinazoline-8-carboxylic acid amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-7-methylisoquinoline | HCID 22250186 | — |
| Reactant | 4-(3-Amino-benzylamino)-quinazoline-8-carboxylic acid amide hydrochloride | HCID 66763358 | — |
| Product | 4-[3-(7-Methyl-isoquinolin-1-ylamino)-benzylamino]-quinazoline-8-carboxylic acid amide | HCID 66762648 | — |
Reaction Steps
The title compound was prepared according to Example 684 starting 4-(3-Amino-benzylamino)-quinazoline-8-carboxylic acid amide hydrochloride and 1-Chloro-7-methyl-isoquinoline at 120° C.:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08637532B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-b54f85f0e8284da99f67ca788ec8647d |
| Source note | uspto-grants-2014_01 |