HRID474839
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
产物
AUXILIARIES
试剂、催化剂与溶剂
CONDITIONS
反应条件
- 温度
- 80 °C
PROCEDURE
实验过程
To the solution of 4-((5-(trifluoromethyl)pyridin-2-yl)oxy)phenethyl carbamimidate, Trifluoroacetate (600 mg, 1.369 mmol) and methyl 2-formyl-3-(2-methoxypyrimidin-5-yl)propanoate (246 mg, 1.095 mmol) in 1,4-dioxane (6 mL) was added K2CO3 (757 mg, 5.48 mmol). The mixture was heated with a microwave reactor at 80° C. for 0.5 h. Purification via MDAP then afforded the title compound (2 mg, 0.293 yield). LCMS: rt=3.09 min, [M+H+]=500
WORKUP
后处理
- customPurification via MDAP