p-Toluenesulfonic acid monohydrate → HCID 178505404, compound

Participants

Reaction Steps

A mixture of 108 (170 mg, 0.38 mmol) and TsOH.H2O (72 mg, 0.38 mmol) in MeOH (5 mL) and water (1 mL) was heated at reflux for 2 h. After solvent was removed in vacuo, the residue was purified by preparative HPLC to give 60 mg (43%) of I-28 as white solid.

Provenance & Evidence