Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 475248Generated: October 25, 2026

(1-(tetrahydro-2H-pyran-2-yl)-1H-benzo[d]imidazol-5-yl)methanamine → HCID 178461873, compound

https://huagongshe.com/reaction/475248

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1-(tetrahydro-2H-pyran-2-yl)-1H-benzo[d]imidazol-5-yl)methanamineHCID 46739877—
ReactantHCID 178420295HCID 178420295—
ProductHCID 178461873HCID 178461873—

Reaction Steps

N2-(1H-Benzimidazol-5-ylmethyl)-N4-[5-[(trans)-2-phenylcyclopropyl]-1H-pyrazol-3-yl]pyrimidine-2,4-diamine (I-27) prepared analogously starting from 91 and condensing with (1-(tetrahydro-2H-pyran-2-yl)-1H-benzo[d]imidazol-5-yl)methanamine (28) and subsequently removing the pyran in accord with the procedure in steps 6 and 7 of example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08637537B2
Source datasetuspto-grants-2014_01
ORD IDord-0420996c9c45422ab5d32a4566c3e557
Source noteuspto-grants-2014_01