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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 475289Generated: October 30, 2026

HCID 71529203, compound → HCID 86694755, compound

https://huagongshe.com/reaction/475289

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 71529203HCID 71529203—
ReactantHCID 86694756HCID 86694756—
ProductHCID 86694755HCID 86694755—

Reaction Steps

N2-((1H-indol-4-yl)methyl)-N4-(5-(tetrahydrofuran-2-yl)-1H-pyrazol-3-yl)pyrimidine-2,4-diamine (I-119) and N2-(1H-indol-4-yl)methyl)-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-5-fluoropyrimidine-2,4-diamine (I-120) were prepared analogously except 2-chloro-N-(5-(trans-2-(2-fluorophenyl)cyclopropyl)-1H-pyrazol-3-yl)pyrimidin-4-amine was replaced with 83 and 55, respectively

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08637537B2
Source datasetuspto-grants-2014_01
ORD IDord-7376b6b2475546d9a31ab07c89483a78
Source noteuspto-grants-2014_01