HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-amino-3-bromo-2-fluorobenzonitrile → 6-Bromo-2-chloro-5-fluoroquinazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-amino-3-bromo-2-fluorobenzonitrile | HCID 2761199 | — |
| Reactant | 6-Bromo-2-chloro-8-methoxyquinazoline | HCID 46738296 | — |
| Product | 6-Bromo-2-chloro-5-fluoroquinazoline | HCID 57461136 | — |
Reaction Steps
6-bromo-2-chloro-5-fluoro-quinazoline is prepared analogously to WO 2007/117607 or to the above-mentioned synthesis of 6-bromo-2-chloro-8-methoxy-quinazoline starting from 2-amino-5-bromo-6-fluoro-benzonitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08637549B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-29843d3dc15349dc9dfb4e5790aa0626 |
| Source note | uspto-grants-2014_01 |