Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Urea | HCID 1176 | — |
| Reactant | 3-Amino-6-chloropyridine-2-carbaldehyde | HCID 57461139 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178517174 | HCID 178517174 | — |
Reaction Steps
3-amino-6-chloro-pyridine-2-carbaldehyde (3.2 g, 13.0 mmol) is mixed thoroughly with urea (7.8 g, 130 mmol) and heated to 180° C. in the preheated oil bath for 3 h. Then the reaction mixture is suspended in H2O, the precipitate is filtered off and 6-chloro-3H-pyrido[3,2-d]pyrimidin-2-one is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08637549B2 |
|---|
| Source dataset | uspto-grants-2014_01 |
|---|
| ORD ID | ord-807bfca2af4c47ee97433cf8fbcbe68d |
|---|
| Source note | uspto-grants-2014_01 |
|---|
