反应详情

温度

70 °C

To a stirred solution of (4-bromo-2-(propan-2-ylideneaminooxy)phenyl)(2-(diethoxymethyl)phenyl)methanone (Compound 3a) (18 g) in ethanol (50 mL) at 70° C. was added 2M hydrochloric acid (25 mL). The mixture was stirred at 70° C. for 20 min forming a thick suspension. Water (500 mL) was added and the resultant solid filtered off and dried in vacuo at 50° C. to give the title compound (12 g).

1. customforming a thick suspension
2. filtrationthe resultant solid filtered off
3. customdried in vacuo at 50° C.