HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric acid magnesium salt (1:1) → HCID 178505794, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| Reactant | 4-Fluoro-alpha-(4-fluorophenyl)benzenemethanamine | HCID 10955039 | — |
| Reactant | 2-(6-Bromobenzo[d]isoxazol-3-yl)benzaldehyde | HCID 86675995 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178505794 | HCID 178505794 | 72% |
Reaction Steps
To a stirred solution of 2-(6-bromobenzo[d]isoxazol-3-yl)benzaldehyde (compound 7) (2 g) in dichloromethane (33 mL) was added bis(4-fluorophenyl)methanamine (1.74 g) and anhydrous magnesium sulfate and stirred under nitrogen at room temperature for 18 h. Filtration and evaporation of the filtrate and crystallisation from dichloromethane-methanol gave the title compound (2.4 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08637551B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-4015796ac46d441698388cef6c323ce6 |
| Source note | uspto-grants-2014_01 |