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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 475558Generated: October 26, 2026

Ethyl 2-chloroacetoacetate → Ethyl [2-(3,4-dimethoxyphenyl)oxazol-4-yl]acetate

https://huagongshe.com/reaction/475558

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-chloroacetoacetateHCID 11858—
Reactant3,4-DiethoxybenzamideHCID 340342—
ProductEthyl [2-(3,4-dimethoxyphenyl)oxazol-4-yl]acetateHCID 86633755—

Reaction Steps

Using ethyl 2-chloroacetoacetate and 16 g of 3,4-diethoxybenzamide and following the procedure of Reference Example 5, 3.8 g of ethyl [2-(3,4-dimethoxyphenyl)oxazol-4-yl]acetate was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08637559B2
Source datasetuspto-grants-2014_01
ORD IDord-e67960cef2ea42b7b4b36219bd4de4c1
Source noteuspto-grants-2014_01