2-Bromopropane → HCID 68983051, compound

HRID 475599Notes

Reaction equation

[F:1][CH:2]([F:28])[O:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[C:10](=[O:27])[CH2:11][CH2:12][C:13]1[N:14]=[C:15]([C:18]2[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[C:20]([OH:26])[CH:19]=2)[O:16][CH:17]=1.Br[CH:30]([CH3:32])[CH3:31]>>[F:28][CH:2]([F:1])[O:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[C:10](=[O:27])[CH2:11][CH2:12][C:13]1[N:14]=[C:15]([C:18]2[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[C:20]([O:26][CH:30]([CH3:32])[CH3:31])[CH:19]=2)[O:16][CH:17]=1

Participants

Reactant 2

HCID 63582-Bromopropane

HCID 68983175HCID 68983175, compound

Product 1

HCID 68983051HCID 68983051, compound

Procedure

Using the compound obtained in Example 270 and 2-bromopropane, white powdery 1-(2-difluoromethoxyphenyl)-3-[2-(3-isopropoxy-4-methoxyphenyl)oxazol-4-yl]propan-1-one was obtained following the procedure of Example 3.

Sources & evidence

ORD record: ord-6e42a8be6f944729be7d02838ce05565
Source dataset: uspto-grants-2014_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08637559B2

Reaction notes

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