2-Bromopropane → HCID 57855798, compound

HRID 475616Notes

Reaction equation

[F:1][CH:2]([F:28])[O:3][C:4]1[CH:27]=[CH:26][CH:25]=[CH:24][C:5]=1[C:6]([NH:8][CH2:9][C:10]1[N:11]=[C:12]([C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[C:17]([OH:23])[CH:16]=2)[O:13][CH:14]=1)=[O:7].Br[CH:30]([CH3:32])[CH3:31]>>[F:28][CH:2]([F:1])[O:3][C:4]1[CH:27]=[CH:26][CH:25]=[CH:24][C:5]=1[C:6]([NH:8][CH2:9][C:10]1[N:11]=[C:12]([C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[C:17]([O:23][CH:30]([CH3:32])[CH3:31])[CH:16]=2)[O:13][CH:14]=1)=[O:7]

Participants

Reactant 2

HCID 63582-Bromopropane

HCID 57855721HCID 57855721, compound

Product 1

HCID 57855798HCID 57855798, compound

Procedure

Using the compound obtained in Example 321 and 2-bromopropane, white powdery 2-difluoromethoxy-N-[2-(3-isopropoxy-4-methoxyphenyl)oxazol-4-ylmethyl]benzamide was obtained following the procedure of Example 3.

Sources & evidence

ORD record: ord-38845d08b2174cbfb94f735d696994e3
Source dataset: uspto-grants-2014_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08637559B2

Reaction notes

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