HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 58075657, compound → HCID 58075835, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 58075657 | HCID 58075657 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 58075835 | HCID 58075835 | 99.3% |
Reaction Steps
To a solution of 2-chloro-4-(methylamino)-8-phenyl-7,8-dihydroquinazolin-8-ol (20 mg) in EtOAc (5 mL) was added 5% Pd/C (6 mg), and the resulting suspension was stirred under a hydrogen balloon for 1 h. The reaction mixture was filtered through a pad of Celite to give the title compound as a colorless oil (20 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08637525B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-7ab19487b56146cdb7433819e533e11b |
| Source note | uspto-grants-2014_01 |