HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thioacetic acid, O-ethyl ester → (E)-ethyl-5-(3-methoxy-4-tert-butyldimethylsilyloxyphenyl)-3-oxopent-4-enothioate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thioacetic acid, O-ethyl ester | HCID 136711 | — |
| Reactant | (2E)-3-{4-[(tert-butyldimethylsilyl)oxy]-3-methoxyphenyl}prop-2-enoic acid | HCID 11185931 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | (E)-ethyl-5-(3-methoxy-4-tert-butyldimethylsilyloxyphenyl)-3-oxopent-4-enothioate | HCID 131731171 | 60% |
Reaction Steps
The title compound was prepared in the same manner as in Step 1 of Example C-1, except that an equimolar amount of each of trans-3-methoxy-4-tert-butyldimethylsilyloxy-cinnamic acid prepared in Step 1 of Example C-10 and ethyl thioacetate was used in place of trans-cinnamic acid and ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08637674B2 |
| Source dataset | uspto-grants-2014_01 |
| ORD ID | ord-523f6e87e5b340d98de8364de117ef24 |
| Source note | uspto-grants-2014_01 |