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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 476257Generated: October 25, 2026

1-(4-Fluorophenyl)cyclobutanecarboxylic acid → (R)-2-(7-(1-(4-fluorophenyl)-N-methylcyclobutanecarboxamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid

https://huagongshe.com/reaction/476257

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Fluorophenyl)cyclobutanecarboxylic acidHCID 16769017—
Reactantpropyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetateHCID 86655417—
Product(R)-2-(7-(1-(4-fluorophenyl)-N-methylcyclobutanecarboxamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acidHCID 53248760—

Reaction Steps

The title compound was prepared using analogous procedures described in Example 1 (Method A) from 1-(4-fluorophenyl)cyclobutanecarboxylic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 435.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08637671B2
Source datasetuspto-grants-2014_01
ORD IDord-a0728bbecc164894ab0dc63ee6fc5013
Source noteuspto-grants-2014_01