2,2-Diphenylacetyl chloride → HCID 67310782, compound

HRID 476265Notes

Reaction equation

HRID 476265 reaction equation
[C:1]1([CH:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:8](Cl)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:17][NH:18][C@H:19]1[CH2:38][N:23]2[C:24]3[C:29]([C:30]([CH2:31][C:32]([O:34]CCC)=[O:33])=[C:22]2[CH2:21][CH2:20]1)=[CH:28][CH:27]=[CH:26][CH:25]=3>>[C:1]1([CH:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:8]([N:18]([CH3:17])[C@H:19]2[CH2:38][N:23]3[C:24]4[C:29]([C:30]([CH2:31][C:32]([OH:34])=[O:33])=[C:22]3[CH2:21][CH2:20]2)=[CH:28][CH:27]=[CH:26][CH:25]=4)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 746372,2-Diphenylacetyl chlorideHCID 86655417propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate

Product 1

HCID 67310782HCID 67310782, compound

Procedure

The title compound was prepared using analogous procedures described in Example 2 (Method B) from diphenylacetyl chloride and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 453.

Sources & evidence

ORD record
ord-b1e1c8a751c74d0da8423ddfbc5cd751
Source dataset
uspto-grants-2014_01
Patent number
US08637671B2

Reaction notes

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