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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 47660Generated: October 28, 2026

Methyl 2-hydroxy-3-phenylpropanoate → 2-{3,5-Dibromo-4'-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-biphenyl-4-yloxy}-3-phenyl-propionic acid methyl ester

https://huagongshe.com/reaction/47660

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-hydroxy-3-phenylpropanoateHCID 518800—
ReactantHCID 9915604HCID 9915604—
Product2-{3,5-Dibromo-4'-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-biphenyl-4-yloxy}-3-phenyl-propionic acid methyl esterHCID 10439812—

Reaction Steps

The title compound was prepared from 3,5-dibromo-4′-[5-methyl-2-(4-trifluoromethyl-phenyl)-oxazol-4-yl]-biphenyl-4-ol, and 3-phenyllactic acid methyl ester in substantially the same manner, as described in Example 7, and was obtained as a white solid, mp 70-72° C.; MS m/e 713 (M+);

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06699896B1
Source datasetuspto-grants-2004_03
ORD IDord-974ffee9d4864284a9c22034d5735e22
Source noteuspto-grants-2004_03