反应详情

A solid mixture of 9 g flavanone, 7.2 g 3-acetylaminobenzaldehyde and 5 drops piperidine is heated at 150°-160° C. for 3 hours. After allowing to cool, the crude brown glass is dissolved in chloroform and eluted from silicagel with chloroform. The pale yellow oil, obtained on evaporation of the solvent is crystallized from hexane and ethyl acetate to give 3(3-acetylaminobenzylidene)-flavanone as a cream coloured solid; m.p. 172°-173° C.

1. temperatureis heated at 150°-160° C. for 3 hours
2. temperatureto cool
3. washeluted from silicagel with chloroform
4. customThe pale yellow oil, obtained on evaporation of the solvent
5. customis crystallized from hexane and ethyl acetate