HCID 14771304, compound → 2-(Cyclohexyloxy)aniline

HRID 476734Notes

Reaction equation

HRID 476734 reaction equation
[CH:1]1([O:7][C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[N+:14]([O-])=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1>[Pd].CO>[CH:1]1([O:7][C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[NH2:14])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 1

HCID 14771304HCID 14771304, compound

Product 1

HCID 147713052-(Cyclohexyloxy)anilineYield 90.7%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

Fifty ml of a methanol solution containing 3.7 g of 2-cyclohexyloxynitrobenzene and 0.2 g of 5% palladium on carbon was stirred at room temperature under a hydrogen atmosphere for catalytic reduction. The catalyst was removed by filtration, and the filtrate was evaporated off to give 2.9 g of 2-cyclohexyloxyaniline as pale brown crystals.

Workup

  1. customThe catalyst was removed by filtration
  2. customthe filtrate was evaporated off

Sources & evidence

ORD record
ord-84576895b9bb4a4fbcf6eb39bb9315ff
Source dataset
uspto-grants-1989_12
Patent number
US04885367

Reaction notes

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