HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropylamine → HCID 178471875, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | Ethyl 3-ethoxy-2-(3-chloro-2,4,5-trifluorobenzoyl)acrylate | HCID 54402571 | — |
| Solvent | tert-Butanol | HCID 6386 | — |
| Product | HCID 178471875 | HCID 178471875 | — |
Reaction Steps
A solution of 2.7 g (8.0 mmol) of ethyl 2-(3-chloro-2,4,5-trifluorobenzoyl)-3-ethoxyacrylate, 0.46 g (8.0 mmol) of cyclopropylamine, and 40 ml of dry t-butanol is stirred at 45° C. for 21/2 hours. The mixture is cooled to room temperature and used without purification in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04885386 |
| Source dataset | uspto-grants-1989_12 |
| ORD ID | ord-1c9082ed52ad425b8d05009c749d5ac2 |
| Source note | uspto-grants-1989_12 |