13-Oxabicyclo[10.1.0]tridecane → Cyclododecanone

HRID 476779Notes

Reaction equation

[O:1]1[CH:3]2[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH:2]12.[Cl-].[Li+]>>[C:2]1(=[O:1])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1

Participants

Reactant 2

HCID 924813-Oxabicyclo[10.1.0]tridecane

HCID 433294Lithium Chloride

Product 1

HCID 13246CyclododecanoneYield 94%

Conditions

Temperature: 200 °C

Procedure

25 g of epoxy-cyclododecane and 1 g of lithium chloride were dissolved in 20 g of N,N'-dimethyl ethylene urea and the solvent was stirred at 200° C. for 6 hours. The reaction mixture was analyzed to have a 94% yield of cyclododecanone.

Sources & evidence

ORD record: ord-7ae9b31cdbc147aa95cadb7d1820ee09
Source dataset: uspto-grants-1989_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04885397

Reaction notes

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