13-Oxabicyclo[10.1.0]tridecane → Cyclododecanone

HRID 476780Notes

Reaction equation

HRID 476780 reaction equation
[O:1]1[CH:3]2[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH:2]12.[Cl-].[Li+]>CN1CCCC1=O>[C:2]1(=[O:1])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1

Participants

4

Reactant 2

HCID 924813-Oxabicyclo[10.1.0]tridecaneHCID 433294Lithium Chloride

Product 1

HCID 13246CyclododecanoneYield 93.5%

Reagents, catalysts & solvents 1

HCID 13387N-methyl-2-pyrrolidoneSolvent

Conditions

Temperature
200 °C

Procedure

A solution containing 25 g of epoxy-cyclododecane, 1 g of lithium chloride, and 20 g of N-methyl-2-pyrrolidone was stirred at 200° C. for 6 hours. The reaction mixture contained 93.5% yield of cyclododecanone.

Sources & evidence

ORD record
ord-908967b062ab4a69ab3a755d13761e3b
Source dataset
uspto-grants-1989_12
Patent number
US04885397

Reaction notes

Loading…