Lithium Chloride → Cyclohexadecanone

HRID 476783Notes

Reaction equation

HRID 476783 reaction equation
[O:1]1[CH:3]2[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH:2]12.[Cl-].[Li+]>CN1CCCC1=O>[C:2]1(=[O:1])[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3]1

Participants

4

Reactant 2

HCID 433294Lithium ChlorideHCID 19838537HCID 19838537, compound

Product 1

HCID 75695CyclohexadecanoneYield 98.9%

Reagents, catalysts & solvents 1

HCID 13387N-methyl-2-pyrrolidoneSolvent

Conditions

Temperature
200 °C

Procedure

A mixture containing 10.5 g of epoxy-cyclohexadecane, 10 g of N-methylpyrrolidone, and 0.5 g of lithium chloride was stirred at 200° C. for 6 hours. With a 100% conversion, a 98.9% yield of cyclohexadecanone was obtained.

Sources & evidence

ORD record
ord-347fa5dd23b648d6ab30a23638a4a096
Source dataset
uspto-grants-1989_12
Patent number
US04885397

Reaction notes

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