Water → HCID 14324491, compound

Participants

Reaction Steps

1.0 kg of ethyl pivaloylacetate was dissolved in 1.0 liter of ethanol, and 320 g of hydrazine hydrate was dropwise added thereto while cooled with water. After completion of the addition, the reaction was carried out overnight at room temperature, and then 5.0 liter of water was added thereto and stirred. The crystal as precipitated was filtered out under reduced pressure and fully washed with water, and then this was further washed with a little amount of methanol and dried with air. Yield: 812 g.

Provenance & Evidence