Chloroacetonitrile → HCID 19837050, compound

HRID 476883Notes

Reaction equation

HRID 476883 reaction equation
[Cl:1][C:2]1[CH:13]=[C:12]2[C:5]([NH:6][CH:7]=[C:8]2[CH2:9][CH2:10][NH2:11])=[CH:4][CH:3]=1.Cl[CH2:15][C:16]#[N:17]>O1CCCC1>[Cl:1][C:2]1[CH:13]=[C:12]2[C:5](=[CH:4][CH:3]=1)[NH:6][CH:7]=[C:8]2[CH2:9][CH2:10][NH:11][CH2:15][C:16]#[N:17]

Participants

4

Reactant 2

HCID 7856ChloroacetonitrileHCID 773795-Chlorotryptamine

Product 1

HCID 19837050HCID 19837050, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Using the procedure of Step A of Example 22, 21.4 g of 5-chlorotryptamine, 7.7 ml of chloroacetonitrile and 18.1 ml of 1,5-diaza[5,4,0]undec-5-ene in 210 ml of tetrahydrofuran were reacted to obtain 19.3 g of the expected product melting at 80° C.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-fc3db97302eb4fb0bf01cd82f89963ec
Source dataset
uspto-grants-1989_12
Patent number
US04886802

Reaction notes

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