反应详情

73.5 g of 3-methyl-2-chloroquinoline in 102 ml of hydrazine hydrate are heated under reflux for 3 hours. The reaction mixture is cooled and the solid is filtered off, washed and dried. The crystalline mass obtained is recrystallized from isopropanol to give 50.5 g of 2-hydrazino-3-methylquinoline melting at 128° C.

1. temperatureunder reflux for 3 hours
2. temperatureThe reaction mixture is cooled
3. filtrationthe solid is filtered off
4. washwashed
5. customdried
6. customThe crystalline mass obtained
7. customis recrystallized from isopropanol