N-(2-Amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)acetamide hydrobromide (1:1) → 4,5,6,7-Tetrahydro-benzothiazole-2,6-diamine dihydrobromide

HRID 476965Notes

Reaction equation

HRID 476965 reaction equation
[BrH:1].C([NH:5][CH:6]1[CH2:15][CH2:14][C:9]2[N:10]=[C:11]([NH2:13])[S:12][C:8]=2[CH2:7]1)(=O)C>Br>[BrH:1].[BrH:1].[NH2:13][C:11]1[S:12][C:8]2[CH2:7][CH:6]([NH2:5])[CH2:15][CH2:14][C:9]=2[N:10]=1

Participants

3

Reactant 1

HCID 13670691N-(2-Amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)acetamide hydrobromide (1:1)

Product 1

HCID 136706894,5,6,7-Tetrahydro-benzothiazole-2,6-diamine dihydrobromide

Reagents, catalysts & solvents 1

HCID 260Hydrogen BromideSolvent

Procedure

3 g (0.01 Mol) of 6-acetylamino-2-amino-4,5,6,7-tetrahydro-benzthiazole-hydrobromide are dissolved in 20 ml of semi-concentrated hydrobromic acid and refluxed for 6 hours. The solution is then concentrated by evaporation and the residue recrystallised from methanol.

Workup

  1. temperaturerefluxed for 6 hours
  2. concentrationThe solution is then concentrated by evaporation
  3. customthe residue recrystallised from methanol

Sources & evidence

ORD record
ord-566f7237ee0140398b6a8b81b94aa309
Source dataset
uspto-grants-1989_12
Patent number
US04886812

Reaction notes

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