1,1'-Carbonyldiimidazole → 2-Imidazolidinone, 1-(3-phenyl-2-propenyl)-3-(3-pyridinyl)-, (E)-

HRID 477000Notes

Reaction equation

HRID 477000 reaction equation
[CH2:1]([NH:10][CH2:11][CH2:12][NH:13][C:14]1[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=1)/[CH:2]=[CH:3]/[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[C:20](N1C=CN=C1)(N1C=CN=C1)=[O:21]>>[CH2:1]([N:10]1[CH2:11][CH2:12][N:13]([C:14]2[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=2)[C:20]1=[O:21])/[CH:2]=[CH:3]/[C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

Participants

3

Reactant 2

HCID 682631,1'-CarbonyldiimidazoleHCID 14834214(E)-N-cinnamyl-N'-(3-pyridyl)ethylenediamine

Product 1

HCID 64507052-Imidazolidinone, 1-(3-phenyl-2-propenyl)-3-(3-pyridinyl)-, (E)-Yield 70.3%

Procedure

By treating 2.53 g of (E)-N-cinnamyl-N'-(3-pyridyl)ethylenediamine and 1.63 g of carbonyldiimidazole in the same manner as in Example 106-(2), 1.96 g of (E)-1-cinnamyl-3-(3-pyridyl)-2-imidazolidinone was obtained.

Sources & evidence

ORD record
ord-075e43bb6cbb45479bcee236818041fd
Source dataset
uspto-grants-1989_12
Patent number
US04886817

Reaction notes

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