HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 1516513, compound → HCID 70395373, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 1516513 | HCID 1516513 | — |
| Reactant | 5-Amino-1-cyclopropyl-6,7,8-trifluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | HCID 13910947 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 70395373 | HCID 70395373 | — |
Reaction Steps
In the same manner as described in Example 16 (1), a mixture of 5-amino-1-cyclopropyl-6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid, trans-3-aminomethyl-4-methylpyrrolidine, and dimethylformamide was stirred at room temperature for 24 hours to give 5-amino-7-(trans-3-aminomethyl-4-methyl-1-pyrrolidinyl)-1-cyclopropyl-6,8-difluoro-1,4-dihydro4-oxoquinoline-3-carboxylic acid, which was recrystallized from ethanol, m.p. 223°-225° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04886810 |
| Source dataset | uspto-grants-1989_12 |
| ORD ID | ord-4eb8072f920d44298fc949a48ec915b8 |
| Source note | uspto-grants-1989_12 |