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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 477108Generated: October 30, 2026

Methyl 2-(4-(2-oxopropyl)phenoxy)acetate → N-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-methyl-thiazol-4-yl)ethanamine

https://huagongshe.com/reaction/477108

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(4-(2-oxopropyl)phenoxy)acetateHCID 13851156—
Reactant2-Amino-1-(2-methyl-1,3-thiazol-4-yl)ethanolHCID 16768496—
ProductN-[2-(4-Carbomethoxymethoxyphenyl)-1-methylethyl]-2-hydroxy-2-(2-methyl-thiazol-4-yl)ethanamineHCID 19974370—

Reaction Steps

Prepared analogously to Example 13 by reaction of 2-hydroxy-2-(2-methyl-thiazol-4-yl)ethanamine with 1-(4-carbomethoxymethoxyphenyl)propan-2-one followed by purification of the base on a silica gel column using ethyl acetate/methanol=9:1 as eluant.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04886814
Source datasetuspto-grants-1989_12
ORD IDord-e0c62b717a2248ffbc4dc4b20ecb36c0
Source noteuspto-grants-1989_12