HCID 10497335, compound → HCID 14155093, compound

HRID 477228Notes

Reaction equation

HRID 477228 reaction equation
[CH2:1]([S:8][C:9]1[N:23]=[C:12]2[N:13]=[C:14]([O:17][CH2:18][C:19](F)(F)F)[CH:15]=[CH:16][N:11]2[N:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)C>[CH2:1]([S:8][C:9]1[N:23]=[C:12]2[N:13]=[C:14]([O:17][CH2:18][CH3:19])[CH:15]=[CH:16][N:11]2[N:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 10497335HCID 10497335, compound

Product 1

HCID 14155093HCID 14155093, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

This material was prepared by heating 2 benzylthio-5-(2,2,2-trifluoroethoxy)-1,2,4-triazolo[1,5-a]pyrimidine in boiling ethanol. The hot mixture was filtered and the filtrate was concentrated. The crude product was recrystallized from isopropanol to yield the desired product as a solid, m.p. 115°-117° C. IR and 1H NMR spectra were in agreement with the assigned structure.

Workup

  1. customThis material was prepared
  2. filtrationThe hot mixture was filtered
  3. concentrationthe filtrate was concentrated
  4. customThe crude product was recrystallized from isopropanol

Sources & evidence

ORD record
ord-2c392175643a44a290036a0f55ed9686
Source dataset
uspto-grants-1989_12
Patent number
US04886883

Reaction notes

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