HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 47725Generated: October 26, 2026
Hydrochloric Acid → (2R)-2-amino-3-(3-carboxyphenyl)-1-propanol hydrochloride
https://huagongshe.com/reaction/47725
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-[(1R)-2-hydroxy-1-(3-carboxybenzyl)ethyl]acetamide | HCID 69699113 | — |
| Product | (2R)-2-amino-3-(3-carboxyphenyl)-1-propanol hydrochloride | HCID 69885138 | — |
Reaction Steps
The process is performed as in Example 2, starting with 1.96 g of N-[(1R)-2-hydroxy-1-(3-carboxybenzyl)ethyl]acetamide in 14 cm3 of aqueous 6N hydrochloric acid heated at a temperature in the region of 100° C. for 17 hours. After an identical work-up, 2.16 g of (2R)-2-amino-3-(3-carboxyphenyl)-1-propanol hydrochloride are obtained in the form of a white solid melting at 194° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06699895B2 |
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| Source dataset | uspto-grants-2004_03 |
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| ORD ID | ord-b206d38bc336441e843339c043259704 |
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| Source note | uspto-grants-2004_03 |
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