HRID47736

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID4311764

Sodium borohydride (Na(BH4))

H4BNa

结构：CCOC(=O)[C@H](Cc1cccc([N+](=O)[O-])c1)NC(C)=O

HCID53755981

未命名化合物

PRODUCTS

生成物

结构：CC(=O)N[C@H](CO)Cc1cccc([N+](=O)[O-])c1

HCID69698133

未命名化合物

收率 95.4%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

The process is performed as in Example 2, starting with 7.15 g of ethyl (2S)-2-(acetylamino)-3-(3-nitrophenyl)propanoate and 1.46 g of sodium borohydride in 70 cm3 of ethanol. After an identical work-up, 5.8 g of N-[(1S)-2-hydroxy-1-(3-nitrobenzyl)-ethyl]acetamide are obtained in the form of a white solid melting at 131° C.